End Organ Damage In Hypertension
نویسندگان
چکیده
منابع مشابه
MicroRNAs are involved in end-organ damage during hypertension.
Even in the new millennium, arterial hypertension remains a serious condition, with considerable morbidity and mortality worldwide. Crucial in managing the disease is not only lowering arterial blood pressure but also preventing or treating the typical end-organ damage caused by long-lasting and inadequately treated hypertension. In the past decade, it has been shown that microRNAs (miRs) are i...
متن کاملTarget Organ Damage in Hypertension
This special issue is related to the main concern in hyper-tensive disease: the target-organ damage. The selected papers approach some aspects of renal and cerebral disease associated to hypertension but the principal focus is on the arterial vessel as the main organ involved in hypertensive patients. Although hypertensive cardiopathy is not specifically included in this issue, the heart diseas...
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PURPOSE OF REVIEW This review highlights recent clinical studies demonstrating the contribution of aldosterone to cardiovascular mortality, vascular dysfunction, and renal injury in the context of advances in our understanding of the molecular biology of aldosterone. RECENT FINDINGS Mineralocorticoid receptor antagonism reduces mortality in patients with congestive heart failure and following...
متن کاملTarget Organ Damage in Essential Hypertension
Epidemiological data suggests that hypertension remains a major modifiable risk factor for cardiovascular disease in Western countries. The prevalence of the disease among adults in Slovenia aged 25–64 years is between 40–50% (CINDI, 2006). The early detection and severity of typical target organ damage and secondary diseases are key determinants of cardiovascular prognosis in patients sufferin...
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Hypertension generally brings to mind hemodynamic mechanisms, increased peripheral vascular resistance, the laws of Ohm or Hagen-Poisseule, and perhaps targetorgan damage mediated through acceleration of atherosclerosis, vasculitis, or other concomitant processes. However, innate and acquired adaptive cellular or even antibodymediated immunity plays an active role in the pathogenesis of hyperte...
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ژورنال
عنوان ژورنال: Deutsches Aerzteblatt Online
سال: 2010
ISSN: 1866-0452
DOI: 10.3238/arztebl.2010.0866